21c Museum Hotel, Durham, North Carolina

Founded by art collectors and preservationists Laura Lee Brown and Steve Wilson, the 21c Museum Hotel Durham in North Carolina began as a reimaging of the Shreve, Lamb & Harmon-designed Hill building, which originally housed the Durham Bank and Trust Company. “Our main inspiration was the 1937 Hill building itself,” explains designer Deborah Berke of New York-based Deborah Berke Partners.